Izun Oral Care began in 2000 as Izun Pharmaceuticals Corporation to identify and test natural bio-active compounds that exhibited powerful wound-healing properties. The Company’s research team identified a synergistic mixture of Sambucus nigra, Echinacea purpurea and Centella asiatica for further testing as active ingredients for various health care applications. The exceptional results of their research formed the basis for filing of a patent portfolio of 50 issued and pending patents with oral care claims beginning in 2002 for their bio-active platform. Since founding, the Company has conducted over 16 dental clinical studies in the treatment of gingivitis, periodontitis, and oral ulcerative lesions. All of the studies have shown statistical significance confirming the efficacy and safety of the patented bio-active blend to address a broad range of oral care indications.
In June 2014, Izun Oral Care was spun-out from Izun Pharmaceuticals Corporation as a separate Delaware company to focus on oral care applications of the core technology. The Company’s two lead products, PeriActive® Rinse and PerioPatch® (an innovative hydrogel patch), provide a breakthrough opportunity to address advanced gum disease (also called periodontal disease), a growing problem of epidemic proportions affecting 50% of American adults over age 30. PeriActive Rinse and PerioPatch have already been launched into the professional channel in the US and Israel with enthusiastic support by key opinion leaders in the dental community.